Incubator Accessories
Diagnostic Biosystems FLUOROMOUNT/PLUS Fluoromount/Plus™
Fluoromount/Plus™ is an innovative, aqueous-based mounting medium designed especially for the permanent preservation of fluorescent specimens. Fluoromount/Plus™is to be used with tissue sections stained with a multitude of fluorescent dyes. This product is compatible with FITC, phycoerythrin, phycocyanin and allophycocyanin. It can also be used with other fluorescent markers such as Texas Red and rhodamine.\n\nMounting tissue specimens stained with fluorescent dyes.
Diagnostic Biosystems IGA-FITC IgA-FITC
This antibody reacts with the alpha chain of human IgA. Traces of contaminating antibodies have been removed by solid phase absorption with human plasma proteins. This antibody is well suited for tissue section staining but may also be used for other applications.
Diagnostic Biosystems MYELOPEROXIDASE Myeloperoxidase
This antibody reacts with human myeloperoxidase. It stains granules of neutrophils, granulocytesin spleen, bone marrow, tonsil and blood smears.
Diagnostic Biosystems BOB1 BOB.1 (SP92)
Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNAbinding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.
Diagnostic Biosystems CYCLIN D1 Cyclin D1 (EP12)
Cyclin D1 belongs to the Cyclin D family. Cyclin D1 is required for the cell cycle G1/S transition. Amplification or overexpression of Cyclin D1 plays a pivotal role in the development of various human cancers including breast cancer, colon cancer, melanoma, prostate cancer and lymphoma. It is useful to differentiate mantle cell lymphoma from small cleaved cell lymphoma. Rabbit monoclonal antibodies to Cyclin D1 showed the highest sensitivity to detect this antigen in formalin fixed paraffin embedded tissue as compared to several other clones.
Diagnostic Biosystems CDX2 CDX2 (EP25)
The caudal-related homeodomain protein 2, CDX-2, is a transcription factor which is expressed in the intestine and is thought to play an important role in the proliferation and differentiation of intestinal epithelial cells. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas, intestinal metaplasia of the stomach and intestinal type gastric cancer. In human colorectal cancer, the expression of both CDX2 and carbonic anhydrase 1, a gene regulated by CDX2, is reduced or absent. CDX-2 is one of the important regulators in defining pathways for coordinate control of drug metabolism in the gastrointestinal tract.
Diagnostic Biosystems 10X CITRATE BUFFER PH 70 10X Citrate Buffer For Heat Induced Epitope Recovery, pH 7.0
10X Citrate Buffer For Heat Induced Epitope Recovery, pH 7.0 is designed for use during the heat induced epitope retrieval (HIER) step prior to immunohistochemistry on formalin-fixed paraffin embedded tissue sections. The use of this buffer in combination with heat (often by microwave, water bath, or pressure cooker) has been shown to restore the antigenicity of proteins modified during the formalin fixation of tissue. This buffer is supplied as a 10X stock solution.
Diagnostic Biosystems UNOVUE MOUSE HRP DETECTION RE UnoVue™ Mouse HRP Detection Reagent
UnoVue Mouse HRP Detection Reagent is suitable for use with mouse all Ig antibodies, both monoclonal and polyclonal. The reagents can be used for manual staining or with automated staining instruments and are well suited for multiplex immunohistochemical staining assays.
Diagnostic Biosystems CD5 CD5 (SP19)
This antibody recognizes CD5, which is a transmembrane protein, is found on 95%of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Occasionally, CD5 antigen is also expressed on a subset of B cells. Mantle cell lymphomas(same as diffuse centrocytic lymphomas) are CD5(+) while the follicle center cell lymphoma are CD5(-).
Diagnostic Biosystems HRP LABEL Glial Fibrillary Acidic Protein (GFAP)
This antibody recognizes a protein of ~50kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.
Diagnostic Biosystems MUCIN 5AC Mucin 5AC/Gastric Mucin
This antibody reacts with a 1000 kDa protein and recognizesthe peptide core of gastric mucin M1. Mucins are high molecular weight glycoproteins with 80% carbohydrates and 20% core protein. Gastric mucin M1 antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either reexpression of the peptide core of gastric mucin in the adult colon or changes in the glycosylation pattern of mucin, which expose the hidden M1 antigen.
Diagnostic Biosystems TRICHOME STAIN Trichome Stain
The Trichrome Stain Kit (Modified Masson’s) is intended for use in the histological visualization of collagenous connective tissue fibers in formalin-fixed tissue sections.
Diagnostic Biosystems PERMABLUE/HRP PermaBlue/HRP
PermaBlue/HRP is a substrate-chromogen system designed to be used for either IHC or ISH when utilizing horseradish peroxidase. PermaBlue/HRP can be permanently mounted to produce a strong azure blue color that can be easily distinguished from other stains.